HRAS p.Q61L Reference Standard
CBP10286
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| Introduction | |
| Format | Genomic DNA |
| Description | HRAS Q61L is hotspot mutation that lies within the GTP binding domain of the Hras protein (UniProt.org). Q61L results in decreased Hras GTPase activity and leads to transFormation of cells in culture (PMID: 23487764, PMID: 3510078). |
| Technical Data | |
| DNA Change | c.182A>T |
| AA Change | p.Q61L |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 67.86% |
| Transcript | ENST00000397596 |
| Cosmic ID | COSM498 |
| Chr position(GRCh37) | chr11:533874 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
